Paediatric Osteosarcoma Patient Data with Physeal Breach and Metastasis Outcomes

A single-centre, retrospective cohort study of 32 paediatric osteosarcoma patients. The dataset includes patient demographics, tumour characteristics, physeal breach status, and pulmonary metastasis outcomes, supporting a study published on figshare. The data was contributed by Zichen Lin and last updated in May 2026.

Use Cases

• Predicting pulmonary metastasis risk based on physeal breach status.
• Training logistic regression models for metastasis using clinical and imaging variables.
• Investigating angiogenic activity via VEGF immunohistochemistry data referenced in the study.
• Validating imaging biomarkers for tumour aggressiveness in skeletally immature patients.

Strengths

• Includes data from 32 paediatric patients with detailed clinical follow-up.
• Contains results from a complementary xenograft mouse model (143B cells in nude mice).
• Primary outcome (pulmonary metastasis) analysed with multivariable logistic regression.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect single-centre bias inherent to the study design.

Provenance

Source

figshare

Collection Method

Single-centre, retrospective cohort study.

Freshness

Last updated 2026-05-05 05:28:19; freshness should be verified.