18F-Fluciclovine PET Background Uptake in Head Tissues for 20 Glioma Patients

20 patients with suspected malignant glioma underwent 18F-fluciclovine PET/CT imaging to establish a baseline for physiological tracer uptake. Standardized uptake values were measured in 24 predefined head regions, with dynamic evaluation in 15 patients and a comparison to 11C-methionine PET in 8 patients. The dataset, authored by Yumi Abe and last updated in June 2026, provides quantitative background data to aid in distinguishing normal from pathological uptake in brain tumor assessment.

Use Cases

• Establishing a normative baseline for 18F-fluciclovine PET interpretation based on SUV measurements in 24 head regions.
• Comparing amino acid tracer uptake patterns between 18F-fluciclovine and 11C-methionine PET based on the subset of 8 patients with both scans.
• Analyzing temporal uptake dynamics in brain and glandular tissues based on time–activity curves from 15 patients.
• Training or validating machine learning models for automated segmentation or anomaly detection in PET neuro-oncology images.

Strengths

• Includes quantitative SUV measurements for 24 predefined anatomical regions, providing structured data.
• Contains a direct comparison of two PET tracers (18F-fluciclovine vs. 11C-methionine) in a subset of 8 patients.
• Features dynamic imaging data with time–activity curves for 15 patients, showing temporal uptake patterns.
• Dataset is openly licensed under CC-BY-4.0, facilitating reuse and sharing.

Limitations

• Row count and specific column-level documentation are absent; field semantics must be inferred after download.
• The dataset is small in scale (126.3 KB), suggesting it contains summary statistics or a limited sample rather than raw image data.
• Data is derived from a single cohort of 20 patients with suspected glioma, which may limit generalizability.

Provenance

Source

figshare, authored by Yumi Abe.

Collection Method

Retrospective analysis of 18F-fluciclovine PET/CT images from 20 patients with suspected malignant glioma.

Freshness

Last updated 2026-06-02 05:40:38; freshness should be verified.