Review of Piezo1 Ion Channel Role in Orthodontic Tooth Movement

A review document summarizing recent research developments on the Piezo1 ion channel. The document discusses Piezo1's role as a mechanosensitive receptor in alveolar bone remodeling during orthodontic tooth movement. Yan Yan authored the review, which was last updated on May 8, 2026.

Use Cases

• Summarize molecular pathways for Piezo1-mediated bone remodeling based on the review content.
• Identify potential therapeutic targets for orthodontic therapy based on the discussion of Piezo1 inhibition.
• Review the balance between osteogenesis and osteoclastogenesis in response to mechanical stimuli as described in the document.

Strengths

• The document is a focused review on a specific biological target (Piezo1) in a clinical context (orthodontics).
• It summarizes recent research developments, suggesting it includes current findings.
• The file is openly licensed under CC-BY-4.0.

Limitations

• The dataset is a single 314.8 KB DOCX file, indicating a very limited scope and likely a short review article.
• Column-level documentation is absent; the content structure must be inferred after download.
• Row count is unknown, which confirms it is not a structured data collection.

Provenance

Source

figshare

Freshness

Last updated 2026-05-08 05:56:21; freshness should be verified.