Mouse Liver Toxicity Data from Perinatal Bisphenol S Exposure Study

A 327.1 KB document published on figshare in June 2026 by Mengfen Pan. It describes experimental data from a study investigating the effects of perinatal exposure to Bisphenol S (BPS) on offspring mice. The data likely includes measurements of liver injury, serum enzyme levels, lipid profiles, and ferroptosis markers.

Use Cases

• Analyzing the relationship between BPS exposure levels and liver injury markers based on serum ALT and AST levels mentioned in the description
• Studying the impact of endocrine disruptors on lipid metabolism based on triglyceride, cholesterol, and LDL/HDL measurements
• Investigating ferroptosis as a mechanism of toxicity based on indicators of iron accumulation, mitochondrial damage, and oxidative stress

Strengths

• The dataset is associated with a detailed experimental methodology described in the document, including control and three BPS exposure groups (0.2, 2, and 20 mg/L)
• The study investigates a specific mechanistic pathway (ferroptosis) and includes validation via co-exposure with a ferroptosis inhibitor (Fer-1)
• The data is published under a CC-BY-4.0 license, allowing for reuse and redistribution

Limitations

• Column-level documentation is absent; field semantics must be inferred from the descriptive text after download
• Row count is unknown, which may limit suitability assessment for quantitative analysis
• The data is contained in a DOCX file (327.1 KB), suggesting a limited scope and likely being a summary or report rather than raw tabular data

Provenance

Source

figshare

Collection Method

Experimental data from a controlled animal study where pregnant mice were exposed to BPS via drinking water.

Freshness

Last updated 2026-06-04 22:02:05; freshness should be verified