Data Sheet 1: Pregnane X Receptor (NR1I2) Deficiency in Mice

Salah Edden Amini authored a review document integrating data from whole-body and tissue-specific Nr1i2-deficient mouse models. The 24.7 KB document, last updated on 2026-05-12, discusses the role of the pregnane X receptor in intestinal inflammation and homeostasis. It is shared under a CC-BY-4.0 license on figshare.

Use Cases

• Reviewing evidence on the role of NR1I2 in intestinal inflammation based on the described mouse model studies.
• Comparing phenotypes of whole-body versus tissue-specific Nr1i2 deficiency as discussed in the document.
• Investigating the context-dependent effects of pharmacological NR1I2 activation for therapeutic strategy development.

Strengths

• Document is shared under a permissive CC-BY-4.0 license.
• The review integrates data from multiple experimental approaches, including whole-body and tissue-specific mouse models.

Limitations

• The dataset is a 24.7 KB document, indicating a limited scope of raw data.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

Salah Edden Amini

Collection Method

Review and integration of published studies.

Freshness

Last updated 2026-05-12 04:19:34; freshness should be verified.