Prenatal Stress Effects on Adult Stress Recovery in Rodent Model

Branden G. Verosky's dataset on figshare contains experimental results examining how prenatal stress influences behavioral and transcriptional responses to repeated adult stress in rodent offspring. The data includes endpoints for anxiety-like and social behavior, corticosterone levels, and gene expression across brain regions like prefrontal cortex, hippocampus, amygdala, and hypothalamus. It was last updated on May 13, 2026.

Use Cases

• Modeling the interaction between prenatal and adult stress exposures based on the factorial design described.
• Analyzing sex-specific gene regulation patterns during stress recovery phases mentioned in the results.
• Correlating transient corticosterone responses with region-specific transcriptional changes across the brain regions listed.
• Investigating latent vulnerability to psychopathology based on selective behavioral differences described in the discussion.

Strengths

• Dataset is openly licensed under CC-BY-4.0.
• Description details a controlled 2x2 factorial experimental design with both sexes.
• Analysis covers multiple endpoints: behavior, endocrine output, and transcriptional data across four brain regions.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 139.5 KB, indicating limited scope.

Provenance

Source

Branden G. Verosky

Collection Method

Experimental data from a rodent model study involving prenatal restraint stress and repeated adult restraint stress.

Freshness

Last updated 2026-05-13 04:41:15; freshness should be verified.