Mouse Study Data on Ferulic Acid's Effect on Ulcerative Colitis

Experimental data from a study of 60 male Kunming mice investigating the preventive effect of ferulic acid on dextran sulfate sodium-induced ulcerative colitis. The dataset includes quantified measurements of inflammatory mediators, antioxidant enzymes, fecal biomarkers, and gut microbiota composition. The data was authored by Zheng Zhong and uploaded to figshare in April 2026.

Use Cases

• Modeling the relationship between antioxidant enzyme activities (SOD, GSH-Px, CAT) and disease severity based on described measurements.
• Analyzing gut microbiota shifts (e.g., Muribaculaceae, Clostridia) in response to preventive treatment based on 16S rRNA sequencing results.
• Correlating inflammatory mediator levels (IL-1β, IL-6, IL-2, IL-10) with histopathological outcomes described in the study.
• Comparing the efficacy of ferulic acid versus prednisone treatment based on the quantified biomarker data.

Strengths

• Includes data from a controlled animal experiment with six distinct treatment groups.
• Measures a multi-faceted panel of biomarkers covering inflammation, oxidative stress, and microbiome composition.
• Released under a permissive CC-BY-4.0 license for reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small (208.9 KB), indicating limited scope.

Provenance

Source

figshare

Collection Method

Data generated from a laboratory experiment involving histopathology, ELISA kits, and 16S rRNA sequencing.

Time Range

Experimental timeframe not specified.

Freshness

Last updated 2026-04-13 05:48:57; freshness should be verified.

Geography

Study location not specified.