Prognostic Impact of NF1 Mutation in Korean Glioblastoma Cohort

95 glioblastoma patient records from a Korean cohort, analyzed for survival factors using next-generation sequencing data. The dataset includes demographic, clinical, and genetic variables, with findings on NF1 mutation and MGMT promoter status. It was authored by Ryong Heo and last updated on 2026-05-21.

Use Cases

• Predicting overall survival based on NF1 mutation status mentioned in the description
• Analyzing the correlation between unmethylated MGMT promoter status and patient outcomes
• Investigating demographic factors like age and BUN levels as prognostic indicators
• Conducting multivariable Cox regression analysis on clinical-genomic data

Strengths

• Includes 95 patient records with linked clinical and genetic data
• Specific findings on 11 samples (11.5%) with NF1 mutations are reported
• Statistical results (p-values) for key variables like age and MGMT status are provided

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• The sample size for the NF1 mutation group is noted as limited (N=11)

Provenance

Source

figshare

Collection Method

Data obtained from the Oncomine comprehensive assay for 95 glioblastoma patients.

Freshness

Last updated 2026-05-21 04:35:52; freshness should be verified

Geography

Korean cohort