Propranolol Effects on Memory and Molecular Pathways in an AD-like Rat Model

Behavioral and molecular data from a study investigating the effects of propranolol on scopolamine-induced cognitive deficits in Wistar rats. The dataset includes results from Novel Object Recognition and Elevated Plus Maze tests, along with analyses of synaptic plasticity markers, mitochondrial function, oxidative stress, and inflammation. The data was uploaded to figshare by an author named Pinky and last updated on 2026-05-29.

Use Cases

• Train models to predict cognitive outcomes based on molecular marker levels mentioned in the description.
• Analyze correlations between behavioral test results (recognition index, anxiety-like behavior) and biochemical parameters (Aβ1–42, ROS, GFAP).
• Study the CaMKII/CREB–BDNF/PKMζ signaling cascade in relation to drug-induced memory improvements.

Strengths

• Dataset is associated with a detailed experimental protocol described in the source document.
• License is clearly stated as CC-BY-4.0, permitting reuse with attribution.

Limitations

• The dataset is small (581.1 KB), indicating limited scope.
• Row count and column-level documentation are unknown, requiring manual inspection after download.
• The primary data file is a DOCX document, which may require parsing to extract structured data.

Provenance

Source

figshare

Collection Method

Data was generated from a controlled laboratory experiment on Wistar rats, as described in the document.

Freshness

Last updated 2026-05-29 06:13:22; freshness should be verified.