Quadrupedal Training Evidence Review for Post-Stroke Rehabilitation

A 2010-2025 scoping review synthesizes evidence on quadrupedal-derived training for adult stroke rehabilitation. Jan A. Kuipers authored this review, which includes 18 studies such as five randomized controlled trials and one case study. It maps outcomes to the International Classification of Functioning domains and analyzes intervention types, dosage, safety, and feasibility.

Use Cases

• Analyze the relationship between intervention types (e.g., kneeling-based, treadmill-based) and reported outcomes like trunk control and balance improvements.
• Compare total dosage and supervision data across studies to inform clinical protocol design.
• Map study findings to International Classification of Functioning (ICF) domains for standardized outcome reporting.
• Assess safety and feasibility metrics, including adherence rates and absence of serious adverse events.
• Examine mechanistic evidence linking quadrupedal loading to activation of spinal networks and proximal muscles.

Strengths

• 18 included studies provide a foundational evidence base.
• Covers research from 2010 to 2025, offering a 15-year perspective.
• Follows JBI and PRISMA-ScR guidelines for systematic scoping review methodology.
• Incorporates stakeholder input from survivors, clinicians, and researchers.

Limitations

• Small evidence base of only 18 primary studies limits statistical power for meta-analysis.
• Evidence is synthesized from published literature; contains no primary patient-level data.
• Temporal coverage is for publication dates, not the timeline of the clinical interventions studied.

Provenance

Source

Jan A. Kuipers via figshare.

Collection Method

Scoping review conducted via systematic search of five databases and additional sources.

Time Range

Literature published from 2010 to 2025.

Freshness

Last updated in April 2026, representing a recent synthesis.