Cardiac CT Visceral Fat Volumes and Heart Failure Risk in Asymptomatic Adults

A retrospective study of 3,094 asymptomatic adults undergoing health screening cardiac CT scans. The dataset, authored by Cheng-Chun Yang and last updated in May 2026, quantifies intrathoracic visceral fat depots and their association with incident heart failure over a median follow-up of 10.3 years.

Use Cases

• Predicting incident heart failure risk based on quantified epicardial adipose tissue (EAT) volume.
• Analyzing associations between peri-aortic root fat (PARF) volume and heart failure with preserved ejection fraction (HFpEF).
• Modeling the interaction between body mass index (BMI) and intrathoracic fat accumulation across sexes.
• Developing risk stratification models using optimal fat volume cutoffs (e.g., 71.37 cm³ for EAT).

Strengths

• Includes data from 3,094 participants with a median follow-up of 10.3 years.
• Quantifies multiple specific fat depots (EAT, PARF, TAT) using a semi-automated CT method.
• Provides hazard ratios and optimal cutoffs for key associations, such as a 1.23 hazard ratio per Z-score increase for EAT.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect geographic or demographic bias inherent to the single health screening cohort.

Provenance

Source

figshare

Collection Method

Retrospective analysis of cardiac CT scans and echocardiography from health screening.

Freshness

Last updated 2026-05-28 04:52:40; freshness should be verified.