Fluvibactin Biosynthesis Gene Regulation in Vibrio fluvialis

A 251.8 KB PDF from figshare details the genetic regulation of fluvibactin, a catechol siderophore, in the pathogen Vibrio fluvialis. Qian Cheng authored this CC-BY-4.0 licensed study, which identifies a 16-gene cluster and its regulation by quorum sensing regulators AphA and HapR. The data was last updated on May 4, 2026.

Use Cases

• Modeling gene expression networks based on the described 9 transcriptional units.
• Analyzing protein-DNA interactions based on promoter binding assays.
• Studying bacterial virulence factors based on fluvibactin's role in infection.
• Investigating quorum sensing mechanisms based on AphA and HapR regulatory roles.

Strengths

• The description provides a specific gene count (16 genes organized into 9 transcriptional units).
• The study confirms direct binding of regulators AphA and HapR to gene promoters.
• Animal experiments link fluvibactin production to increased bacterial loads in mice.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is a single 251.8 KB PDF, offering limited scope for direct computational analysis.

Provenance

Source

figshare

Collection Method

Experimental study using qPCR, reporter assays, EMSA, DNase I footprinting, and 5′ RACE.

Freshness

Last updated 2026-05-04 05:32:48; freshness should be verified.