Regenerative Potential of CD200- Hair Follicle Bulge Subpopulations

Ting Sun's research article investigates the hair-regenerative capability of CD200- and KRT15-expressing human hair follicle bulge cells. The study integrates phenotypic characterization, transcriptomic profiling, and in vivo hair regeneration assays. It was published on figshare on April 23, 2026, under a CC-BY-4.0 license.

Use Cases

• Identifying biomarkers for hair follicle stem cell potency based on CD200 expression levels.
• Training models to predict hair regenerative potential from transcriptomic profiles of bulge cells.
• Optimizing culture systems for hair follicle bulge cells based on correlations with CD200 expression.
• Refining functional interpretations of cellular heterogeneity within the hair follicle bulge.

Strengths

• Integrates multiple experimental methods: phenotypic characterization, transcriptomic profiling, and in vivo assays.
• Focuses on a specific and biologically relevant subpopulation (CD200- bulge cells).
• Provides insights directly applicable to optimizing cell-based hair regeneration approaches.

Limitations

• The dataset is a 414.1 KB PDF, which is a small document rather than a primary data repository.
• Row count and column-level documentation for any underlying data are absent.
• Data freshness should be verified, as the last update is dated in the future (2026-04-23).

Provenance

Source

figshare, authored by Ting Sun.

Collection Method

Research involving freshly isolated and cultured human hair follicle bulge cells, analyzed through phenotypic, transcriptomic, and in vivo assays.

Freshness

Last updated 2026-04-23 05:34:38; freshness should be verified.