Zebrafish Social Memory: Neuronal Activation in Telencephalic Nuclei

The dataset quantifies c-fos protein expression in four telencephalic nuclei (Dm, Dl, Vv, Vd) of male zebrafish following agonistic encounters. It compares neuronal activation across groups with different social memory states, including individuals who remembered an opponent, those treated with an amnesic agent, and a no-interaction control. The dataset is derived from immunohistochemical analysis.

Use Cases

• Compare c-fos immunopositive cell counts in the Vv nucleus between agonistic encounter groups and the no-interaction control group.
• Analyze activation levels in the Dl nucleus to differentiate individuals facing a remembered versus an unremembered opponent.
• Correlate behavioral evidence of opponent recognition with quantified neuronal activation across the Dm, Dl, Vv, and Vd nuclei.
• Investigate the role of the social decision-making network by evaluating c-fos expression patterns in the four studied telencephalic nuclei.

Strengths

• Data is derived from a controlled long-term memory paradigm with specific experimental groups (remembered, amnesic-treated, no-interaction).
• Quantifies neuronal activation in four distinct telencephalic nuclei (Dm, Dl, Vv, Vd) of the zebrafish brain.
• Findings are published and peer-reviewed, providing a basis for understanding neuronal processes in social memory.

Limitations

• The dataset is small (1.8 MB), suggesting a limited sample size of zebrafish subjects.
• Data is presented in a DOCX document, which is not a standard structured format (e.g., CSV) for quantitative analysis and may require manual extraction.
• The study focuses on male zebrafish only, limiting generalizability to females.

Provenance

Source

figshare, authored by Luciano Cavallino.

Collection Method

Immunohistochemical quantification of c-fos protein in zebrafish brain nuclei following controlled agonistic encounters.

Freshness

Last updated on 2026-03-20.