Rat Neuropathic Pain Study Data on rTMS Effects on Spinal Cord and Sciatic Nerve

A 2.6 MB document details a study where repetitive transcranial magnetic stimulation alleviated pain behaviors in a rat neuropathic pain model. The research includes behavioral testing and molecular, histological, and ultrastructural analyses of the spinal cord and sciatic nerve. Daniel Youngsuk Kim authored this dataset, which was last updated on May 7, 2026.

Use Cases

• Analyzing the effects of rTMS on pain-related behaviors like thermal hyperalgesia and mechanical allodynia based on behavioral testing results.
• Investigating changes in pro-inflammatory markers such as CD86, Iba-1, and TRPV1 in the spinal cord and sciatic nerve following rTMS treatment.
• Studying peripheral nerve structural recovery based on ultrastructural analysis metrics like myelin thickness and G-ratio.
• Examining the relationship between rTMS treatment and mitigation of muscle atrophy, indicated by gastrocnemius muscle mass and cross-sectional area.

Strengths

• The dataset is associated with a detailed research methodology involving behavioral, molecular, histological, and ultrastructural analyses.
• Results include specific p-values (e.g., p < 0.01 for Iba-1 reduction) indicating statistical significance for many findings.
• The document is licensed under CC-BY-4.0, permitting open sharing and adaptation.

Limitations

• The dataset is a 2.6 MB DOCX file; the underlying raw data tables, column definitions, and row counts are not provided.
• Data is derived from a specific rat model of neuropathic pain, which may limit direct translation to human clinical contexts.
• Description metadata is limited; actual data quality and structure require manual inspection after download.

Provenance

Source

figshare, authored by Daniel Youngsuk Kim.

Collection Method

Data was generated from a rat neuropathic pain model established by unilateral sciatic nerve ligation, with evaluations via behavioral testing and molecular/histological/ultrastructural analyses.

Freshness

Last updated 2026-05-07 04:46:19; freshness should be verified.