Resident Eosinophil Counts in COPD Patients and Healthy Controls

A prospective observational pilot study from January to June 2025 includes data from 27 patients with stable chronic obstructive pulmonary disease (COPD) and 10 healthy controls. The dataset, authored by Wei Sun and shared under a CC-BY-4.0 license, contains flow cytometry results for eosinophil subtypes, pulmonary function tests, and cytokine levels. It was last updated on May 25, 2026.

Use Cases

• Identify biomarkers for COPD prediction based on the absolute number of resident eosinophils.
• Analyze the relationship between eosinophil subtype ratios and COPD pathophysiology.
• Correlate pulmonary function test results with specific inflammatory cell profiles.
• Validate flow cytometry signatures for distinguishing resident from inflammatory eosinophils in a clinical cohort.

Strengths

• Includes a control group of 10 healthy individuals for comparison.
• Provides a specific predictive AUC value (0.856) and odds ratio (0.231) for a key biomarker.
• Data collection is described as a prospective observational study with a defined time range.

Limitations

• The dataset is small, with only 37 total participants (27 patients, 10 controls).
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Prospective observational study involving blood sample collection, eosinophil isolation, and flow-cytometry analysis.

Time Range

January 2025 to June 2025

Freshness

Last updated 2026-05-25 06:05:54; freshness should be verified.