RIN2 Gene Expression and Function in Chicken Adipogenesis

A research data sheet from 2026 describes the role of Ras and Rab Interactor 2 (RIN2) in chicken fat cell development. Author Wujian Lin presents findings from functional analyses in ICP-1 cells and primary preadipocytes, showing RIN2's effect on proliferation and differentiation. The data sheet highlights RIN2's potential as a genetic target for improving poultry carcass composition.

Use Cases

• Study gene expression patterns during adipocyte differentiation based on the described dynamic expression patterns.
• Investigate the link between cholesterol metabolism and fat accumulation based on the modulation of the cholesterol metabolic pathway.
• Explore genetic targets for reducing abdominal fat in poultry based on the in vivo knockdown results.
• Analyze cellular proliferation and cell cycle progression in preadipocytes based on the functional analyses of RIN2 overexpression and knockdown.

Strengths

• Data sheet is openly licensed under CC-BY-4.0.
• Research includes both in vitro (ICP-1 cells, primary preadipocytes) and in vivo functional analyses.

Limitations

• Dataset size is 54.4 KB, indicating a very limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Research data sheet from functional analyses and transcriptomic profiling.

Freshness

Last updated 2026-04-27 09:29:56; freshness should be verified.