Risk Factors for Finger Replantation Necrosis: A Meta-Analysis of 12 Studies

A systematic review and meta-analysis of 12 observational studies involving 3,645 patients, investigating risk factors for necrosis after finger replantation surgery. The study, authored by Feiyong Yu and last updated in April 2026, was conducted by searching multiple databases including PubMed, Embase, and Web of Science. It calculates pooled odds ratios for factors like smoking, ischemia time, and crush injury using a random-effects model.

Use Cases

• Training predictive models for postoperative necrosis risk based on identified factors like smoking and ischemia time.
• Informing clinical decision-making and perioperative risk assessment protocols for digital replantation.
• Conducting secondary meta-analyses or systematic reviews on surgical complications in microsurgery.
• Benchmarking institutional outcomes against the pooled odds ratios for factors such as thrombosis and vein graft use.

Strengths

• Includes data from 12 studies and 3,645 patients, providing a substantial evidence base.
• Quantifies risk with specific pooled odds ratios (e.g., OR=3.48 for smoking) and 95% confidence intervals.
• Uses a defined methodological protocol, including the Newcastle-Ottawa Scale for quality assessment.
• Has a registered systematic review protocol (PROSPERO CRD420261290184).

Limitations

• The primary data file is a 1.9 MB DOCX document; the underlying tabular data or study-level data is not directly provided.
• Outcome definitions for necrosis were not fully consistent across the included original studies, as noted in the conclusion.
• Row count and column-level documentation for any underlying data are unknown.

Provenance

Source

figshare

Collection Method

Systematic literature search of PubMed, Embase, Web of Science, Cochrane Library, CNKI, Wanfang, and VIP databases.

Time Range

Studies from database indexing to January 1, 2026.

Freshness

Last updated 2026-04-13 05:30:30.

Geography

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