Data Sheet 1_Role of probiotic supplementation in preventing ventilator-associated pneumon

Yan Jiang's 2026 umbrella review synthesizes evidence from 24 meta-analyses of randomized controlled trials involving 92,711 mechanically ventilated patients. The review analyzes the association between probiotic therapy and outcomes like ventilator-associated pneumonia incidence, ICU stay, and mortality. The study protocol is registered with PROSPERO (ID: CRD420251034247).

Use Cases

• Training models to predict clinical outcomes based on synthesized meta-analysis results.
• Analyzing effect size trends for probiotic interventions across multiple systematic reviews.
• Benchmarking methodological quality of systematic reviews using AMSTAR 2 ratings mentioned in the description.

Strengths

• Synthesizes data from 24 meta-analyses covering 92,711 patients, providing a broad evidence base.
• Reports specific quantitative outcomes like odds ratios and weighted mean differences for key clinical metrics.
• Includes a registered study protocol (PROSPERO CRD420251034247) and uses the AMSTAR 2 tool for quality assessment.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The description notes the overall quality of the available evidence remains insufficient to support definitive conclusions.

Provenance

Source

Yan Jiang via figshare.

Collection Method

A comprehensive search across PubMed, Embase, Web of Science, the Cochrane Library, Scopus, and CNKI for systematic reviews published from database inception to July 20, 2025.

Time Range

Systematic reviews from database inception to July 20, 2025.

Freshness

Last updated 2026-03-18 07:44:53; freshness should be verified.

Geography

Global (based on international database search).