Serum Progesterone Levels and Outcomes in 917 Hormone Replacement FET Cycles

A retrospective cohort study of 917 hormone replacement frozen embryo transfer cycles from a single center between 2017 and 2023. The data describes patient groups based on receipt of a single-dose progesterone rescue and analyzes live birth and miscarriage rates relative to pre-transfer progesterone levels. The dataset was authored by Goksu Goc and shared under a CC-BY-4.0 license.

Use Cases

• Analyzing the association between pre-transfer progesterone levels and live birth rates based on the described cohort groupings.
• Investigating miscarriage rates among clinical pregnancies in relation to progesterone levels below 5 ng/mL.
• Exploring outcomes for borderline progesterone cycles (9.1–9.9 ng/mL) with and without rescue intervention.
• Validating assay-specific signals for progesterone thresholds using the described Cobas e411 ECLIA methodology.

Strengths

• Includes data from 917 hormone replacement frozen embryo transfer cycles, providing a substantial clinical cohort.
• Analysis is based on a specific, described institutional protocol and a defined rescue intervention (50 mg IM progesterone).
• Employs multiple statistical methods including multivariable logistic regression and bootstrap resampling as noted in the description.

Limitations

• The dataset is very small (29.9 KB), indicating limited raw data or a summary document rather than a full patient-level dataset.
• Column-level documentation is absent; field semantics must be inferred after download.
• The study is retrospective and single-center, which may limit generalizability.

Provenance

Source

figshare

Collection Method

Single-center retrospective cohort study.

Time Range

2017–2023

Freshness

Last updated 2026-06-01 04:17:41; freshness should be verified.