Data Sheet 1_Serum total bile acids within the normal range are inversely associated with

A clinical study of 631 patients with premature coronary artery disease (PCAD) enrolled from the First Affiliated Hospital of Xi’an Jiaotong University. The dataset likely contains patient-level measurements of serum total bile acid (TBA), inflammatory indices, and coronary lesion severity. It was authored by Heze Fan and last updated on 2026-04 16.

Use Cases

• Modeling the association between serum bile acid levels and coronary lesion severity based on the Gensini score.
• Analyzing the mediating role of inflammatory indices like neutrophil count and C-reactive protein between bile acids and disease outcomes.
• Investigating correlations between systemic immune-inflammation indices (SII, SIRI) and clinical biomarkers in a PCAD cohort.

Strengths

• Includes data from 631 patients with premature coronary artery disease, providing a specific clinical cohort.
• Analysis includes specific regression coefficients (e.g., β = -0.27 for neutrophil count) and confidence intervals for key associations.
• Released under a CC-BY-4.0 license, permitting broad reuse with attribution.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (674.7 KB), indicating limited scope or a focus on summary statistics rather than raw patient records.

Provenance

Source

figshare, authored by Heze Fan.

Collection Method

Patients were enrolled from the First Affiliated Hospital of Xi’an Jiaotong University; associations were assessed using Spearman correlation and logistic/linear regression.

Time Range

null

Freshness

Last updated 2026-04-16 04:19:09; freshness should be verified.

Geography

Data collection likely occurred in Xi'an, China, based on the hospital location.