Data Sheet 1_Sex differences in classic congenital adrenal hyperplasia: a multicenter, rea

Chiara Simeoli's dataset contains a retrospective, multicenter analysis of 123 adult patients with classic congenital adrenal hyperplasia from four Italian tertiary centers. The data includes anthropometric measurements, glucocorticoid therapy details, and biochemical and hormonal parameters, collected to identify sex-specific predictors of disease control. The dataset was last updated on 2026-04-27 and is shared under a CC-BY-4.0 license.

Use Cases

• Compare anthropometric and metabolic profiles between male and female CAH patients based on features like BMI and waist-to-height ratio.
• Identify predictors of uncontrolled disease, such as visceral adiposity and glucose metabolism abnormalities, as described in the analysis.
• Investigate the relationship between glucocorticoid therapy formulations and biochemical control across sexes.
• Analyze sex-stratified hormonal profiles, including androstenedione levels, in relation to clinical outcomes.

Strengths

• Contains data from 123 adult patients (77 females, 46 males) with specific age ranges provided.
• Multicenter design involving four Italian tertiary centers, likely increasing generalizability within that context.
• Includes a range of clinical parameters such as anthropometry, glucocorticoid therapy, and biochemical/hormonal markers.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect geographic bias inherent to the four Italian centers.

Provenance

Source

Chiara Simeoli via figshare.

Collection Method

Retrospective collection of patient records from four Italian tertiary centers.

Freshness

Last updated 2026-04-27 04:14:35; freshness should be verified.

Geography

Italy (four tertiary centers).