Sex Differences in Immune Responses Following Spinal Cord Injury in Mice

A study by Sara Rito-Fernandes uploaded on figshare in 2026 investigates sex-specific immune responses after spinal cord injury (SCI) in a mouse model. The dataset likely contains 1.8 MB of flow cytometry data from blood and spinal cord samples, tracking immune cell populations across acute and chronic injury stages. Functional recovery was assessed using the Basso Mouse Scale and spontaneous void spot assays.

Use Cases

• Compare sex-specific immune cell dynamics based on flow cytometry data from blood and spinal cord.
• Analyze correlations between locomotor recovery (BMS scores) and immune profiles.
• Investigate temporal patterns of myeloid cell infiltration based on the described acute and chronic stages.

Strengths

• Dataset includes flow cytometry data from both peripheral (blood) and local (spinal cord) immune compartments.
• Functional outcomes are measured using the standardized Basso Mouse Scale (BMS).
• Data collection spans both acute and chronic stages of spinal cord injury.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The primary data is embedded within a DOCX file (1.8 MB), which may require extraction.

Provenance

Source

figshare

Collection Method

Experimental data from a preclinical mouse model of spinal cord injury, analyzed via flow cytometry and behavioral assays.

Freshness

Last updated 2026-05-25 04:32:48; freshness should be verified.