Naïve CD4 T Cell Profiles in People with HIV-1 or HIV-2

Spectral flow cytometry profiles of circulating naïve CD4 T cells from people with HIV under antiretroviral therapy. The data includes profiles from individuals treated early in acute or late in chronic HIV-1 infection, people with HIV-2, and age-matched seronegative controls. Authored by Robert Badura and last updated on 2026-05-11, this 2.6 MB dataset is shared under a CC-BY-4.0 license.

Use Cases

• Compare naïve CD4 T cell heterogeneity based on HIV type and treatment timing.
• Investigate the relationship between IL-7 response and proviral DNA levels in HIV-2 infection.
• Analyze imbalances in conventional and regulatory T cell subpopulations in late-treated individuals.

Strengths

• Data includes distinct clinical cohorts (early-treated HIV-1, late-treated HIV-1, HIV-2, elite controllers, seronegative controls).
• Profiling was performed using spectral flow cytometry, a high-dimensional technique.
• Dataset is openly licensed under CC-BY-4.0.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is contained within a PDF file, which may require extraction for analysis.

Provenance

Source

Robert Badura

Collection Method

Spectral flow cytometry profiling of purified naïve CD4 T cells from clinical cohorts.

Freshness

Last updated 2026-05-11 05:25:05; freshness should be verified.