A dataset of 277 shared differentially expressed genes identified through integrative bioinformatics analysis of ulcerative colitis and sarcopenia. The data includes 13 fatty acid metabolism-related genes and results from machine learning feature-ranking that identified PHYH and HSD17B3 as key hub genes. The dataset was created by Beiying Deng and last updated on April 15, 2026.
Use Cases
- Validate diagnostic biomarkers for ulcerative colitis and sarcopenia based on the identified hub genes PHYH and HSD17B3.
- Investigate immune cell infiltration profiles associated with the expression of the identified hub genes.
- Perform unsupervised clustering of ulcerative colitis patients into molecular subtypes based on the 13 fatty acid metabolism-related shared genes.
- Analyze the enrichment of shared genes in immune-, inflammation-, and metabolism-related pathways.
Strengths
- Includes 277 shared differentially expressed genes identified from comparative analysis.
- Identifies 13 specific fatty acid metabolism-related shared genes.
- Results are supported by preliminary experimental validation in a UC cell model and immunohistochemical analysis.
- Data is licensed under CC-BY-4.0 for open reuse.
Limitations
- Row count is unknown, which may limit suitability assessment.
- Column-level documentation is absent; field semantics must be inferred after download.
- The dataset is very small at 2.2 KB, indicating limited scope.
Provenance
- Source
- figshare
- Collection Method
- Integrative bioinformatics analysis with preliminary experimental validation.
- Time Range
- null
- Freshness
- Last updated 2026-04-15 05:22:36; freshness should be verified.
- Geography
- null