SLC10A3 Glioblastoma Research Paper: Transcriptomic and Single-Cell Analysis

A research paper analyzing the role of the SLC10A3 gene in glioblastoma progression and the tumor immune microenvironment. The document, authored by Shuhui Chen and shared under a CC-BY-4.0 license, presents findings from bulk transcriptomic data from TCGA and CGGA cohorts, single-cell RNA sequencing, and in vitro/vivo experiments. It was last updated on May 13, 2026.

Use Cases

• Reviewing the association between SLC10A3 expression and patient prognosis based on TCGA and CGGA cohort analysis
• Studying tumor-immune cell crosstalk based on single-cell RNA sequencing and cell-cell communication analyses
• Investigating macrophage recruitment and M2 polarization in glioblastoma based on in vitro and in vivo experimental results
• Exploring signaling pathways like PI3K-Akt, NF-κB, and HIF-1 linked to SLC10A3 based on functional enrichment analyses

Strengths

• Analysis integrates multiple data types, including bulk transcriptomics, single-cell RNA-seq, and experimental validation
• The document is openly licensed under CC-BY-4.0 for reuse and distribution
• Research includes data from established public cohorts like TCGA and CGGA

Limitations

• The primary data file is a 2.3 MB DOCX document, not a structured dataset; data extraction is required
• Row count and column-level documentation are unknown, limiting direct usability for analysis
• Freshness should be verified as the last update timestamp is in the future (2026-05-13)

Provenance

Source

figshare

Collection Method

Research analysis of public transcriptomic data and original experimental work

Freshness

Last updated 2026-05-13 04:41:14