Case Report: Surgery-Enabled Precision Oncology in an MSI-High Pulmonary Artery Sarcoma

A 13.9 KB case report authored by Akina Nigi details a rare vascular tumor in a 44-year-old man. The report describes long-term survival achieved through molecularly guided immunotherapy, with disease stability for over 65 months. It was uploaded to figshare under a CC-BY-4.0 license and last updated on 2026-04-30.

Use Cases

• Study rare cancer presentation and treatment based on the detailed clinical narrative.
• Analyze immunotherapy response patterns based on the described MSI-high, TMB-high, and low PD-L1 expression status.
• Investigate hereditary cancer syndromes based on the confirmed pathogenic germline MLH1 variant.
• Review surgical and ECMO support strategies for aggressive tumors based on the described right pneumonectomy procedure.

Strengths

• Report provides a detailed clinical timeline with specific survival duration of over 65 months.
• Includes specific molecular biomarkers: MSI-high status, TMB-high, and a pathogenic germline MLH1 variant.
• Case involves a rare tumor type (pulmonary artery sarcoma) in a patient with a complex medical history.

Limitations

• Data consists of a single case report, limiting statistical power and generalizability.
• Row count and column-level documentation are absent; field semantics must be inferred from the text.
• The 13.9 KB file size indicates a very limited scope, containing primarily narrative text.

Provenance

Source

figshare

Collection Method

Clinical case report.

Freshness

Last updated 2026-04-30 04:16:31; freshness should be verified.