PROACT Study: Anal Cancer Survivor Quality of Life Data, 2011-2024

A single-institution ambispective study by Stefania Manfrida includes patients with anal cancer treated between 2011 and 2024. It contains oncologic outcomes and annual quality-of-life assessments up to 5 years post-treatment using EORTC questionnaires. The dataset was last updated on 2026-05-19.

Use Cases

• Analyze associations between patient-reported quality of life and oncologic outcomes based on the study's statistical analyses.
• Model the relationship between late gastrointestinal toxicity and functional outcomes in bowel and sexual domains.
• Compare quality-of-life scores between sexes and age groups relative to the general population.
• Study the long-term impact of intensity-modulated radiotherapy on colostomy-free survival and locoregional relapse.

Strengths

• Median follow-up of 51 months provides longitudinal perspective.
• Includes 3-year and 5-year survival metrics for overall, disease-free, locoregional relapse-free, and colostomy-free survival.
• Quality of life was assessed annually up to 5 years using standardized EORTC QLQ-C30 and QLQ-ANL27 questionnaires.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is from a single institution, which may limit generalizability.

Provenance

Source

Stefania Manfrida via figshare.

Collection Method

Single-institution ambispective study of patients treated with intensity-modulated radiotherapy-based chemoradiotherapy.

Time Range

Patients treated between 2011 and 2024.

Freshness

Last updated 2026-05-19 04:19:04; freshness should be verified.