Data Sheet 1_Synbiotic effects of 2’-fucosyllactose and Bifidobacterium longum subsp. infa

Human milk oligosaccharides (HMOs) are the third most abundant solid component of human milk. This research article by Shijir Xijier Mingat, published on figshare in May 2026, details an in vitro fermentation study modeling the infant gut microbiome. It investigates the synbiotic effects of the HMO 2'-fucosyllactose combined with the probiotic Bifidobacterium longum subsp. infantis M-63.

Use Cases

• Modeling gut microbiota response to prebiotics based on the described pH-controlled single-batch fermenter method.
• Analyzing synbiotic effects on metabolite production based on the described acetate and aromatic lactic acid outputs.
• Studying inter-individual differences in HMO utilization based on the described variation in bifidobacteria prevalence across populations.

Strengths

• The study models a specific physiological process using a pH-controlled single-batch fermenter.
• It directly compares the effects of a prebiotic (2'-FL) alone versus combined with a specific probiotic strain (M-63).
• The dataset is openly licensed under CC-BY-4.0 for reuse.

Limitations

• The dataset is a 798.3 KB PDF research article; the underlying numerical or sequence data is not provided as a separate structured file.
• Column-level documentation is absent; field semantics must be inferred from the text.
• Row count is unknown, which may limit suitability assessment for quantitative analysis.

Provenance

Source

figshare

Collection Method

In vitro fecal fermentation using a pH-controlled single-batch fermenter.

Freshness

Last updated 2026-05-14 14:05:47; freshness should be verified.