Data Sheet 1_Synchronous gastric and appendiceal mucinous adenocarcinomas: a rare case rep

A 4.2 MB clinical case report document authored by Guangchao Liu and last updated in April 2026. The report details the rare synchronous occurrence of gastric and appendiceal mucinous adenocarcinomas in a 66-year-old male patient, including diagnostic imaging, treatment with neoadjuvant chemoimmunotherapy and HIPEC, and a documented shift in molecular phenotype from dMMR/MSI-H to pMMR status.

Use Cases

• Study the clinical presentation and diagnostic challenges of synchronous gastric and appendiceal mucinous adenocarcinomas based on the detailed case description.
• Analyze the impact of neoadjuvant chemoimmunotherapy (XELOX and sintilimab) on tumor biology based on the reported molecular phenotype transition.
• Investigate the management of pseudomyxoma peritonei (PMP) with combined cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) as described in the case.
• Examine the utility of comprehensive preoperative imaging and surgical evaluation for uncommon synchronous malignancies as highlighted in the conclusion.

Strengths

• Provides a detailed clinical narrative of an exceedingly uncommon synchronous malignancy presentation.
• Includes specific molecular analysis results showing a treatment-induced transition from dMMR/MSI-H to pMMR status.
• Document is under a permissive CC-BY-4.0 license, allowing for reuse and analysis.

Limitations

• Row count and column-level documentation are absent; the document's structure and data semantics must be inferred after download.
• The dataset is a single case report (4.2 MB), limiting statistical generalizability.
• Description metadata is limited; actual data quality and formatting require manual inspection of the DOCX file.

Provenance

Source

figshare, authored by Guangchao Liu.

Collection Method

Likely a clinical case report authored by medical professionals.

Time Range

Case presentation timeframe is not specified.

Freshness

Last updated 2026-04 15 04:21:55; freshness should be verified.

Geography

Geographic coverage is not specified.