Randomized Trial Data on Neurolysis and Methylcobalamin for Nerve Injury

Xuwei Hu's 2026 figshare upload contains results from a clinical trial on peripheral nerve injury therapies. The study randomized 90 patients to compare neurolysis monotherapy, methylcobalamin monotherapy, and their combination. It reports outcomes measured at 60 days, including functional scores, nerve conduction velocities, joint mobility, pain severity, and serum cytokine levels.

Use Cases

• Compare total therapeutic efficacy rates (86.67% vs 50.00% vs 53.33%) across the three treatment groups.
• Analyze correlations between serum cytokine levels (NF-κB, TNF-α, IL-6) and functional recovery scores (Carroll Scale).
• Model the relationship between nerve conduction velocity parameters (MCV, SCV, AMP, LAT) and pain severity scores (Global Pain Scale).
• Assess the synergistic effect of combination therapy on joint mobility parameters (AROM/PROM) versus monotherapies.

Strengths

• Data from a randomized clinical trial with 90 patients split into three equal groups (n=30/group).
• Reports multiple quantitative outcome measures: efficacy percentage, conduction velocities, cytokine levels, and pain scores.
• Clear comparative results with statistical significance (P < 0.05) noted for key findings.

Limitations

• Dataset is a 15.2 KB DOCX file containing summarized results, not the underlying raw patient-level data.
• Small sample size of 90 patients limits statistical power for subgroup analyses.
• Temporal coverage is limited to a single 60-day post-treatment measurement point.

Provenance

Source

Xuwei Hu via figshare.

Collection Method

Randomized clinical trial with patients assigned to three treatment groups.

Time Range

Outcomes measured at 60 days post-treatment.

Freshness

Last updated in April 2026.

Geography

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