A 11.3 KB CSV file from figshare, authored by Baoji Hu and last updated in May 2026, synthesizes evidence on the immune checkpoint molecule VISTA in sepsis. The data sheet likely contains information on VISTA's dynamic expression and its biphasic effects during the hyperinflammatory and immunosuppressive phases of the disease. It supports a review evaluating preclinical studies on VISTA-targeted interventions for sepsis therapy.
Use Cases
- Analyzing the stage-specific expression profiles of VISTA in sepsis based on the described dynamic effects.
- Modeling the relationship between VISTA signaling and clinical outcomes like organ injury based on the review's synthesis.
- Identifying potential therapeutic intervention points based on the described mechanisms of VISTA in immune cell function.
Strengths
- File size is precisely 11.3 KB, indicating a focused and manageable dataset.
- The dataset is associated with a detailed, peer-reviewed-style description of VISTA's role in sepsis.
- License is clearly defined as CC-BY-4.0, permitting broad reuse with attribution.
Limitations
- Row count is unknown, which may limit suitability assessment.
- Column-level documentation is absent; field semantics must be inferred after download.
- The dataset's scope is limited to the specific topic of VISTA in sepsis, as indicated by its small size.
Provenance
- Source
- figshare, author Baoji Hu.
- Collection Method
- Likely compiled as a supporting data sheet for a systematic literature review.
- Freshness
- Last updated 2026-05-29 04:46:43; freshness should be verified.