Blumea Balsamifera Extracellular Vesicles miRNA and Pathway Data for Burn Healing

Lei Chen published data on March 19, 2026, investigating Blumea balsamifera-derived extracellular vesicles for burn wound healing. The dataset likely contains miRNA expression patterns from sequencing, network pharmacology predictions for gene targets, and experimental results from mouse models. GC–MS analysis identified 95 components, and Western blot data confirmed changes in PI3K–Akt pathway phosphorylation.

Use Cases

• Predicting cross-kingdom gene targets based on differentially expressed miRNAs from BB-DEVs and leaves
• Analyzing the involvement of the PI3K–Akt pathway in burn healing based on KEGG enrichment results
• Evaluating anti-inflammatory effects based on cytokine level changes (IL-6, TNF-α, IL-10) from in vitro and in vivo experiments
• Identifying chemical components of BB-DEVs based on GC–MS analysis results

Strengths

• GC–MS analysis identified 95 specific components, including terpenes and fatty acids
• KEGG enrichment analysis indicated significant involvement of the PI3K–Akt pathway with a P value < 0.01
• Experimental data includes in vitro and in vivo confirmation of anti-inflammatory effects

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

Data generated from high-throughput miRNA sequencing, network pharmacology analysis, GC–MS, ELISA, and Western blot experiments on a mouse scald model.

Freshness

Last updated 2026-03-19 06:48:13