Two-Year Clinical Trial on Combined Atropine and Orthokeratology for Childhood Myopia

96 children aged 8–12 years participated in a randomized, placebo-controlled, double-blinded, multicenter clinical trial comparing myopia control treatments. The dataset, published by Ying Yuan on figshare, contains results from a 24-month study measuring axial elongation and other ocular parameters. The primary outcome was axial length, examined at baseline and at 6, 12, 18, and 24 months.

Use Cases

• Compare treatment efficacy based on axial elongation data over 24 months
• Analyze subgroup effects based on initial spherical equivalent refraction or age mentioned in the description
• Assess ocular safety by examining changes in tear meniscus height and non-invasive break-up time
• Model the relationship between treatment and pupillary light reflex latency

Strengths

• Data from a 24-month randomized, placebo-controlled, double-blinded clinical trial
• Includes 96 participants with specific inclusion criteria (myopia -1.00D to -4.00D, astigmatism ≤1.5D)
• Primary outcome (axial length) measured at five time points: baseline, 6, 12, 18, and 24 months
• Published under a CC-BY-4.0 license, allowing for reuse and redistribution

Limitations

• Row count and column-level documentation are unknown, which may limit suitability assessment
• The dataset is small (259.0 KB), indicating limited scope and likely summary-level data
• Description metadata is limited; actual data quality and granularity require manual inspection after download

Provenance

Source

figshare, author Ying Yuan

Collection Method

Randomized, placebo-controlled, double-blinded, multicenter clinical trial

Time Range

Study duration of 24 months

Freshness

Last updated 2026-04-30 05:38:42; freshness should be verified.