Meta-Analysis on Cardiac Rehabilitation Outcomes for Heart Failure Patients

A meta-analysis of 19 randomized controlled trials involving 2,025 patients with heart failure with preserved ejection fraction (HFpEF). The study, authored by Fenghong Liu and last updated in May 2026, systematically assesses the impact of exercise-based cardiac rehabilitation on rehospitalization, mortality, and functional capacity. The results are compiled from a systematic review conducted according to PRISMA guidelines.

Use Cases

• Analyze the effect of cardiac rehabilitation on rehospitalization risk based on the reported risk ratio of 0.52.
• Evaluate improvements in functional exercise capacity based on metrics like 6-minute walk distance and peak oxygen uptake.
• Study the relationship between exercise-based intervention and cardiac function parameters like left atrial volume index and peak heart rate.
• Assess the impact on patient-reported outcomes based on the physical functioning scores from the SF-36 survey.

Strengths

• Analysis is based on 19 randomized controlled trials, a substantial number for a meta-analysis.
• Includes data on 2,025 participants, providing a meaningful sample size.
• Reports specific effect estimates like risk ratios and mean differences with 95% confidence intervals.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Data on blood pressure, lipid profile, glycemic control, and cardiovascular mortality were limited or inconsistently reported, precluding meta-analysis for those outcomes.
• Row count is unknown, which may limit suitability assessment for large-scale modeling.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of randomized controlled trials.

Time Range

Literature searches performed through December 2024.

Freshness

Last updated 2026-05-28 06:32:25; freshness should be verified.