Maternal PM2.5 Exposure and Renal Function in a Pregnancy Cohort Study

Wu Yan's dataset on figshare contains results from a cohort study of 1,508 pregnant women investigating the impact of PM2.5 and its components on kidney function. The study estimated PM2.5 exposure levels before and during pregnancy using a satellite spatiotemporal inversion model and measured blood urea nitrogen, serum creatinine, and uric acid at 13 weeks gestation. The dataset was last updated on 2026-05-20.

Use Cases

• Modeling associations between PM2.5 component exposure and serum creatinine levels based on the described regression analyses.
• Investigating the nephrotoxic effects of specific PM2.5 components like organic matter and soil dust based on the study's findings.
• Analyzing temporal patterns of air pollution exposure impact using data from multiple time points before and during pregnancy mentioned in the description.

Strengths

• Includes data from a cohort of approximately 1,500 pregnant women, as stated in the results.
• Exposure estimates are derived from a satellite spatiotemporal inversion model combined with aerosol optical depth, a method described in the study.
• Analyzes multiple renal function markers (BUN, SCr, UA) and specific PM2.5 components (organic matter, soil dust, black carbon).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (280.7 KB), indicating limited scope, likely containing summary results rather than raw individual-level data.

Provenance

Source

figshare, author Wu Yan.

Collection Method

Cohort study using satellite spatiotemporal inversion modeling for exposure estimation and clinical measurements for renal function.

Time Range

Exposure estimated at 4, 8, and 12 weeks before pregnancy and at 13 weeks of gestation.

Freshness

Last updated 2026-05-20 05:45:40; freshness should be verified.