Parkinson's Gait Study: fNIRS Data on 28 Patients with Cue Interventions

Results from a study of 28 Parkinson's disease patients with Freezing of Gait and 28 healthy controls. It compares gait performance and cerebral hemodynamic responses under Rhythmic Visual Cue, Rhythmic Auditory Cue, and combined cue interventions using functional near-infrared spectroscopy.

Use Cases

• Analyze changes in oxyhemoglobin concentration (∆HbO₂) in the Prefrontal Cortex and Primary Somatosensory Cortex across different cueing interventions.
• Evaluate Functional Connectivity strength between specific Regions of Interest like S1-PFC and M1-PFC in PD-FOG patients versus healthy controls.
• Compare gait parameters such as velocity and stride length under RVC, RAC, and RVC+RAC conditions to assess intervention efficacy.
• Investigate the relationship between cortical activation (e.g., in the Premotor Cortex) and enhanced connectivity among ROIs like PFC-MTG and PFC-PMC.

Strengths

• Includes data from 28 PD-FOG patients and 28 matched healthy controls, providing a comparative baseline.
• Measures multiple modalities: gait parameters, cerebral hemodynamic responses (∆HbO₂), and Functional Connectivity across ROIs.
• Examines three distinct cueing interventions (RVC, RAC, RVC+RAC) to isolate their effects.

Limitations

• Small sample size of 28 patients per group limits statistical power and generalizability of findings.
• Data is contained within a 50.9 KB DOCX file, suggesting it is likely a summary or data sheet rather than a raw, structured dataset.
• Specific column definitions, row counts, and raw data values are not provided in the available description.

Provenance

Source

figshare, authored by Ziyao Zhang.

Collection Method

Data collected via walking experiments with gait measurement and fNIRS during different cue interventions.

Freshness

Last updated in March 2026.