Glutathione and Cognitive Performance in Young and Older Adults

A study of 80 participants (40 young, 40 older adults) investigated the relationship between glutathione (GSH) levels and cognitive integrity, effort, and endurance. Data includes GSH measurements via magnetic resonance spectroscopy (HERMES) in the inferior frontal and parietal cortices, collected at baseline and during cognitive tasks. The dataset was authored by Geraldine Rodríguez-Nieto and last updated on 2026-03 18.

Use Cases

• Modeling the relationship between glutathione levels and cognitive performance based on age and brain region.
• Analyzing the modulation of glutathione during sustained cognitive effort as described in the study.
• Investigating correlations between glutathione, GABA, and blood oxygenation (BOLD) signals mentioned in the description.

Strengths

• Includes data from 80 participants with balanced age groups (40 young, 40 older adults).
• Measures glutathione in two specific brain regions (inferior frontal and parietal cortices).
• Data is collected under a CC-BY-4.0 license, permitting open reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The primary data file is a 1.9 MB DOCX document, which may not be a standard structured data format.

Provenance

Source

figshare, authored by Geraldine Rodríguez-Nieto.

Collection Method

Data gathered via magnetic resonance spectroscopy (HERMES) during cognitive tasks.

Time Range

Study period not specified; dataset reflects a single experimental timeframe.

Freshness

Last updated 2026-03-18 07:43:35.

Geography

Geographic coverage of participants is not specified.