3D Cellular Dynamics and Mandibular Morphogenesis in Mouse Embryos at E10.5

A research dataset from figshare describes three-dimensional patterns of cell behaviors during mandible development in mouse embryos at embryonic day 10.5. The data, created by Andreas Dauter, integrates light-sheet fluorescence microscopy, shape quantification, and semi-automated image segmentation to resolve individual cell behaviors. It was last updated on May 18, 2026, and is shared under a CC-BY-4.0 license.

Use Cases

• Analyzing patterns of cell proliferation and mitotic orientation based on 3D microscopy data mentioned in the description
• Modeling relationships between cellular morphology and tissue-wide growth patterns described in the context of mandibular morphogenesis
• Studying mediolateral patterning of cell behaviors at a critical developmental time point (E10.5) as highlighted in the results

Strengths

• Integrates multiple data modalities: light-sheet fluorescence microscopy, shape quantification, and semi-automated image segmentation as described in the methods.
• Focuses on a specific and critical developmental time point: embryonic day 10.5 (E10.5) in mouse mandible development.
• Data is openly shared under a permissive CC-BY-4.0 license, facilitating reuse.

Limitations

• Dataset scale is small at 1.1 MB, which may limit the scope of analysis.
• Column-level documentation is absent; field semantics must be inferred after download from the accompanying DOCX file.
• Row count is unknown, which may limit suitability assessment for statistical modeling.

Provenance

Source

figshare

Collection Method

Data generated by integrating light-sheet fluorescence microscopy, shape quantification, and semi-automated image segmentation of developing mandible tissue.

Time Range

Embryonic day 10.5 (E10.5) in mouse development.

Freshness

Last updated 2026-05-18 05:43:21; freshness should be verified.