TPM-Like Manipulations in Adolescent Female CUMS Rats: Behavioral and Metabolic Data

Data Sheet 1 contains experimental results from a study on Traditional Pediatric Massage-like manipulations in adolescent female rats. The dataset includes behavioral test results, gene expression levels, cytokine measurements, and liver metabolite concentrations from a study with 7-8 rats per group across four conditions. The data was authored by Shaoyun Zhao and last updated on 2026-05-14.

Use Cases

• Analyze correlations between liver metabolite levels and depressive-like behaviors based on L-Aspartic Acid concentration and behavioral test scores.
• Model the relationship between hepatic GHR/IGF-1 pathway expression and hippocampal inflammation based on qRT-PCR and WB measurements.
• Investigate the antidepressant effects of non-pharmacological interventions based on comparisons between TPM-like manipulations and fluoxetine treatment groups.

Strengths

• Data is derived from a controlled animal study with four distinct experimental groups (CON, CUMS, TPM, FLX).
• Multiple measurement modalities are described, including behavioral tests, qRT-PCR, WB, UPLC-MS/MS, and ELISA.
• The dataset is openly licensed under CC-BY-4.0.

Limitations

• The dataset is small, at 298.8 KB, suggesting limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

Shaoyun Zhao via figshare

Collection Method

Experimental data from a controlled animal study using Sprague-Dawley rats subjected to chronic unpredictable mild stress (CUMS) and various interventions.

Freshness

Last updated 2026-05-14 04:26:51; freshness should be verified.