Measles Virus MF-NCR Phylogenetic Profiles Across Four Genotypes

A study analyzing the evolutionary dynamics of the non-coding region between the matrix and fusion protein genes in measles virus. The dataset, authored by Matteo Fracella and last updated in May 2026, includes phylogenetic profiles for genotypes B3, D4, D8, and H1 from various locations and collection periods. It reports sequence variability, with genotype D8 showing the highest proportion of variable sites at 47%.

Use Cases

• Phylogenetic clustering analysis based on the MF-NCR region across different genotypes
• Tracking sequence variability over time and location based on the reported intermixing and divergence estimates
• Comparative evolutionary studies based on the reported average evolutionary divergences (3% for D8, B3, H1 vs 1% for D4)

Strengths

• Includes specific quantitative findings on sequence variability (e.g., 47% variable sites for genotype D8)
• Provides comparative analysis across four major measles virus genotypes (B3, D4, D8, H1)
• Examines data across different locations and collection periods, as mentioned in the description

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data is presented in a 1.0 MB PDF file, which may require extraction for computational analysis

Provenance

Source

figshare

Collection Method

Maximum likelihood phylogenetic analysis performed using Phyml, with evolutionary divergence estimated using MEGA X.

Time Range

Collection periods before the COVID-19 pandemic, specific years not stated.

Freshness

Last updated 2026-05-08 05:54:21; freshness should be verified

Geography

Different locations, specific regions not stated.