Transbronchial Cryobiopsy Safety in Pulmonary Hypertension: A Prospective Cohort Study

74 patients with interstitial lung disease were prospectively studied to assess bleeding risk during transbronchial lung cryobiopsy (TBCB) in the presence of pulmonary hypertension (PH). The dataset, authored by Hadas Gilboa-Sagy and last updated in May 2026, includes quantitative bleeding volume and clinical severity grades, with no significant association found between PH status and bleeding. Results suggest TBCB is safe for patients with mild to moderate PH, providing positive prospective evidence.

Use Cases

• Assessing bleeding risk associated with transbronchial lung cryobiopsy based on pulmonary artery systolic pressure measurements.
• Analyzing the relationship between pulmonary hypertension severity and procedural complications like pneumothorax and hypoxemia.
• Validating safety protocols for bronchoscopic procedures in patients with comorbid interstitial lung disease and cardiovascular conditions.

Strengths

• Prospective blinded cohort study design with 74 consecutive adult patients.
• Primary outcomes include quantitatively measured bleeding volume and clinically graded severity.
• Multivariable log-linear regression was used to validate findings on bleeding risk.

Limitations

• Row count and column-level documentation are unknown, limiting suitability assessment.
• The dataset is small at 156.0 KB, indicating limited scope.
• Data may reflect bias inherent to the single-center prospective study design.

Provenance

Source

Hadas Gilboa-Sagy via figshare

Collection Method

Prospective blinded cohort study of consecutive adult patients with interstitial lung disease referred for transbronchial lung cryobiopsy.

Freshness

Last updated 2026-05-07 05:34:32