Transcriptomic Analysis of 19 Feline Alimentary Lymphoma Cases Across Five Subtypes

19 cases of feline alimentary lymphoma were analyzed via RNA sequencing and split into five phenotypes: small T cell, B cell, CD56+ B cell, Large Granular T cell, and Large Granular NK cell lymphomas. The transcriptomic analysis identified differentially expressed genes, including ADAMTS14, FOXI3, and RAB17, which correlate with aggressive or indolent biological behavior. The dataset was authored by Daniel McGilp and last updated on 2026-05-29.

Use Cases

• Identify gene expression biomarkers for lymphoma aggressiveness based on the reported differentially expressed genes.
• Compare transcriptomic profiles across the five lymphoma phenotypes described in the study.
• Investigate pathways related to extracellular matrix remodelling, transcription factors, and cellular division mentioned in the analysis.
• Validate potential tumor suppressor genes like RAB17, SYNPO2, and GRM4 for indolent lymphoma types.

Strengths

• Analysis is based on RNA sequencing data from 19 distinct clinical cases.
• Data is structured to compare five specific lymphoma phenotypes defined by histomorphology and immunohistochemistry.
• The dataset is openly available under a CC-BY-4.0 license.

Limitations

• The dataset is very small at 56.9 KB, suggesting limited scope or summary-level data.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for certain analyses.

Provenance

Source

figshare, authored by Daniel McGilp.

Collection Method

RNA sequencing and differential gene analysis applied to clinical samples.

Freshness

Last updated 2026-05-29 04:46:56; freshness should be verified.