Data Sheet 1_Transcriptomic and proteomic analyses of the immune responses of C-type lecti

Integrative transcriptomic and proteomic analyses identified 314 immune-related genes and proteins, including 14 C-type lectins, in larvae infected with the fungus Beauveria bassiana. The dataset, published by Shaohua Li on figshare, includes results from RNA-Seq and iTRAQ techniques. A novel lectin, CpIML4, was found to be highly expressed in 5th-instar larval hemolymph and its knockdown significantly decreased fungal resistance.

Use Cases

• Identify candidate insect immune genes for pest management based on transcriptomic and proteomic screening.
• Study the role of C-type lectins in fungal defense based on expression changes after Beauveria bassiana infection.
• Validate gene function through RNA interference experiments based on survival rate and phenotypic change data.
• Compare immune responses across developmental stages based on expression analysis in 5th-instar larvae.

Strengths

• Integrates two complementary data types: transcriptomic (RNA-Seq) and proteomic (iTRAQ) analyses.
• Identifies a specific set of 314 immune-related genes and proteins, including 14 C-type lectins.
• Includes functional validation data from RNA interference experiments showing survival rate impacts.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The primary data is contained within a 3.3 MB PDF, which may require extraction for computational analysis.

Provenance

Source

Shaohua Li via figshare.

Collection Method

Data generated from RNA-Seq and iTRAQ techniques on non-infected and Beauveria bassiana-infected Conogethes punctiferalis larvae.

Freshness

Last updated 2026-03-18 07:38:16; freshness should be verified.

Geography

Likely China, as Conogethes punctiferalis is described as a pest damaging maize in China.