Data Sheet 1 contains transcriptomic data from a study investigating the effects of moderate-intensity continuous training on high-fat diet-induced muscle wasting in mice. The dataset, shared by Weihao Hong on figshare, includes RNA sequencing results from mouse gastrocnemius muscle tissue. The data was last updated on March 18, 2026.
Use Cases
- Identify differentially expressed genes related to muscle atrophy based on the mention of Foxo1, Fbxo32, and Trim63.
- Analyze transcriptional programs for lipid metabolism based on described pathways for fatty acid uptake and β-oxidation.
- Investigate signaling pathway modulation based on the description of FoxO, PI3K–Akt, MAPK, and insulin signaling.
- Explore transcriptomic profiles associated with angiogenesis and calcium signaling processes mentioned in the description.
Strengths
- Dataset is openly licensed under CC-BY-4.0.
- The study design is clearly described, involving a 21-week HFD feeding period and an 8-week MICT intervention.
- Specific molecular targets and pathways (e.g., FoxO, PI3K–Akt) are identified in the description.
Limitations
- The dataset is small at 17.6 KB, indicating limited scope.
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment.
Provenance
- Source
- Weihao Hong via figshare.
- Collection Method
- RNA sequencing of mouse gastrocnemius muscle tissue from an experimental study.
- Freshness
- Last updated 2026-03-18 07:34:54; freshness should be verified.