Data Sheet 1_Treatment patterns and adherence to lipid-lowering therapy, LDL-C control, cl

A retrospective study from 2013 to 2019 analyzed deidentified medical records of 15,258 patients with hypercholesterolemia at high cardiovascular risk in Israel. The data, authored by Matan Azulay and shared on figshare, describes treatment patterns, adherence to lipid-lowering therapy, LDL-C control, clinical outcomes, and healthcare resource utilization. The study concludes that substantial gaps in LDL-C control and treatment adherence were observed across these high-risk populations.

Use Cases

• Analyzing associations between treatment adherence (PDC) and time to clinical outcomes like percutaneous coronary intervention based on the study results.
• Comparing LDL-C control rates across different high-risk patient subgroups (ASCVD, ASCVD-RE, FH) defined in the description.
• Evaluating the impact of combination therapy (e.g., high-intensity statins plus ezetimibe) on LDL-C levels as described in the results.
• Studying patterns of healthcare resource utilization among patients with hypercholesterolemia in a real-world setting.

Strengths

• Includes data from 15,258 patients, providing a substantial cohort for analysis.
• Covers a 7-year time period from 2013 to 2019, allowing for longitudinal observation.
• Reports specific adherence metrics (PDC ≥ 80%) and LDL-C control rates for distinct patient groups.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect geographic bias inherent to its source from a single healthcare system in Israel.

Provenance

Source

Maccabi Healthcare Services medical records, as referenced in the description.

Collection Method

Retrospective analysis of deidentified patient records.

Time Range

2013 to 2019

Freshness

Last updated 2026-04-30 05:41:38; freshness should be verified.

Geography

Israel