Data Sheet 1_Treg cells protect astrocytes from ferroptosis after subarachnoid hemorrhage

Le Huang published a dataset on figshare in May 2026 investigating the protective role of regulatory T cells in astrocytes after subarachnoid hemorrhage. The dataset likely contains transcriptomic sequencing results and experimental measurements from mouse models and in vitro co-culture studies. The 22 MB ZIP file is licensed under CC-BY-4.0.

Use Cases

• Analyze HIF-1α/Hmox1 pathway activation based on transcriptomic profiling mentioned in the description
• Model astrocyte ferroptosis suppression based on experimental co-culture data
• Validate neurobehavioral outcomes linked to Treg cell enhancement after SAH

Strengths

• Dataset includes transcriptomic sequencing data, which suggests high-dimensional molecular profiles
• Experimental design incorporates multiple validation methods: AAV gene manipulation, drug agonists/antagonists, and neurobehavioral testing
• The dataset is 22 MB, indicating a substantial volume of raw or processed data

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data may reflect methodological bias inherent to the specific mouse model and in vitro conditions used

Provenance

Source

figshare

Collection Method

Data generated from mouse models of subarachnoid hemorrhage, in vitro co-culture experiments, and transcriptome sequencing.

Freshness

Last updated 2026-05-22 04:30:55