Two-Year Cognitive Trajectory in COVID-19 Survivors with Acute Neurological Symptoms

A study from Wuhan, China, investigating the two-year impact of acute neurological symptoms on cognitive decline and new-onset symptoms in COVID-19 survivors. The research involved 3,419 hospitalized patients (December 2022–March 2023), with 2,087 completing follow-up and 901 matched pairs analyzed. It was authored by Jiashuo Lin and shared under a CC-BY-4.0 license.

Use Cases

• Analyze risk factors for long-term cognitive decline based on acute neurological symptoms like delirium and brain fog.
• Model the persistence of symptoms such as fatigue and brain fog over a two-year follow-up period.
• Compare the incidence of new-onset symptoms like insomnia and tinnitus between patient groups with and without initial neurological involvement.

Strengths

• Study design includes a large initial cohort of 3,419 hospitalized patients and a propensity score-matched analysis of 901 pairs.
• Provides specific statistical measures of association (aOR, 95% CI) for key findings.
• Follow-up period of two years allows for analysis of long-term symptom persistence.

Limitations

• Data is presented in a DOCX document (30.1 KB), likely as a summary or data sheet; raw structured data is not directly accessible.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the underlying data is unknown, which may limit suitability assessment.

Provenance

Source

figshare, author Jiashuo Lin.

Collection Method

Clinical study enrolling hospitalized patients with confirmed SARS-CoV-2 infection, using cognitive assessments (IQCODE, TICS-40) and multivariable regression.

Time Range

Patient enrollment from December 2022 to March 2023, with a two-year follow-up.

Freshness

Last updated 2026-04 -13 05:47:49; freshness should be verified.

Geography

Wuhan, China.