Venom Gland Transcriptomics and Bioactivity Data for Mesobuthus crucittii Scorpion

Transcriptomic and bioactivity data from the venom gland of the Iranian endemic scorpion Mesobuthus crucittii, published by Masoumeh Baradaran in 2026. The dataset includes results from in silico analysis, molecular docking, and functional assays on a novel hyaluronidase enzyme. It is a small dataset (26.8 KB) shared under a CC-BY-4.0 license.

Use Cases

• Phylogenetic analysis of venom enzymes based on the described transcriptomic sequences.
• Molecular docking studies based on the modeled catalytic and binding domains of the hyaluronidase.
• Comparative analysis of enzyme substrate specificity based on the reported dual activity on hyaluronan and chondroitin sulfate.
• Structural bioinformatics research based on the unique cysteine framework and conserved motifs (GDWW, FPDC, GWGS) identified.

Strengths

• Includes results from multiple analysis methods: transcriptomics, phylogenetic reconstruction, structural modeling, and functional assays.
• Focuses on a novel enzyme with a described unique structural framework of six disulfide bonds.
• Dataset is openly available under a permissive CC-BY-4.0 license.

Limitations

• The dataset is very small (26.8 KB), indicating limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Venom gland transcriptome profiling, in silico analysis, and experimental turbidimetric assays as described.

Freshness

Last updated 2026-06-01 04:19:03; freshness should be verified.

Geography

Iran (scorpion species is Iranian endemic)