μQFR-Based Real-World Cohort Study of Coronary Stenosis Treatment Concordance

This retrospective cohort study includes 242 patients with angiographically intermediate coronary stenosis and μQFR values adjacent to the grey-zone. It assesses the alignment between Murray law-based QFR (μQFR) physiological assessment and treatment strategies, with a median follow-up of 18 months to evaluate target vessel failure outcomes.

Use Cases

• Analyze the association between μQFR-concordant treatment and target vessel failure (TVF) outcomes, including cardiac death and ischemia-driven revascularization.
• Use logistic regression to identify determinants of operator decision-making, such as lesion severity and overall coronary complexity.
• Compare target vessel myocardial infarction and ischemia-driven target vessel revascularization (ID-TVR) rates between μQFR-concordant and discordant treatment groups.
• Evaluate the impact of μQFR values (low: 0.70–0.74; high: 0.86–0.90) on treatment strategy selection (PCI vs. medication).

Strengths

• Study includes 242 patients with angiographically intermediate coronary stenosis.
• Median follow-up period of 18 months for clinical outcome tracking.
• Clear definition of treatment concordance based on μQFR values and intervention type.

Limitations

• Small cohort size of 242 patients limits statistical power for subgroup analyses.
• Retrospective study design may introduce selection bias.
• Specific column-level data and sample data are unavailable for direct analysis.

Provenance

Source

figshare, author Yanfeng Lu.

Collection Method

Retrospective cohort study.

Time Range

Median follow-up of 18 months.

Freshness

Last updated 2026-03-20.